Zika virus infection in immunocompetent pregnant mice causes fetal damage and placental pathology in the absence of fetal infection

Zika virus (ZIKV) infection during human pregnancy may cause diverse and serious congenital defects in the developing fetus. Previous efforts to generate animal models of human ZIKV infection and clinical symptoms often involved manipulating mice to impair their Type I interferon (IFN) signaling, th...

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Detalles Bibliográficos
Autores principales: Szaba, Frank M., Tighe, Michael, Kummer, Lawrence W., Lanzer, Kathleen G., Ward, Jerrold M., Lanthier, Paula, Kim, In-Jeong, Kuki, Atsuo, Blackman, Marcia A., Thomas, Stephen J., Lin, Jr-Shiuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909921/
https://www.ncbi.nlm.nih.gov/pubmed/29634758
http://dx.doi.org/10.1371/journal.ppat.1006994

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