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DRC2/CCDC65 is a central hub for assembly of the nexin–dynein regulatory complex and other regulators of ciliary and flagellar motility

The nexin–dynein regulatory complex (N-DRC) plays a central role in the regulation of ciliary and flagellar motility. In most species, the N-DRC contains at least 11 subunits, but the specific function of each subunit is unknown. Mutations in three subunits (DRC1, DRC2/CCDC65, DRC4/GAS8) have been l...

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Detalles Bibliográficos
Autores principales:	Bower, Raqual, Tritschler, Douglas, Mills, Kristyn VanderWaal, Heuser, Thomas, Nicastro, Daniela, Porter, Mary E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909927/ https://www.ncbi.nlm.nih.gov/pubmed/29167384 http://dx.doi.org/10.1091/mbc.E17-08-0510

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