Cargando…

Clinical Validation of a Serum Protein Panel (FLNA, FLNB and KRT19) for Diagnosis of Prostate Cancer

This study reports on the development of a novel serum protein panel of three prostate cancer biomarkers, Filamin A, Filamin B and Keratin-19 (FLNA, FLNB and KRT19) using multivariate models for disease screening and prognosis. ELISA and IPMRM (LC-MS/MS) based assays were developed and analytically...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ravipaty, Shobha, Wu, Wenfang, Dalvi, Aditee, Tanna, Nikunj, Andreazi, Joe, Friss, Tracey, Klotz, Allison, Liao, Chenchen, Garren, Jeonifer, Schofield, Sally, Diamandis, Eleftherios P, Klein, Eric A, Dobi, Albert, Srivastava, Shiv, Tekumalla, Poornima, Kiebish, Michael A, Vishnudas, Vivek, Sarangarajan, Ranga Prasad, Narain, Niven R, Akmaev, Viatcheslav R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909981/ https://www.ncbi.nlm.nih.gov/pubmed/29682400 http://dx.doi.org/10.4172/2155-9929.1000323

Ejemplares similares

Clinical utility of a serum biomarker panel in distinguishing prostate cancer from benign prostate hyperplasia
por: Kiebish, Michael A., et al.
Publicado: (2021)

Identification of Filamin-A and -B as potential biomarkers for prostate cancer
por: Narain, Niven R, et al.
Publicado: (2016)

Genomic alterations of Tenascin C in highly aggressive prostate cancer: a meta-analysis
por: Mishra, Prachi, et al.
Publicado: (2019)

Upregulation of circFLNA contributes to laryngeal squamous cell carcinoma migration by circFLNA–miR-486-3p-FLNA axis
por: Wang, Jian-Xing, et al.
Publicado: (2019)

Integrated Metabolomics Assessment of Human Dried Blood Spots and Urine Strips
por: Drolet, Jeremy, et al.
Publicado: (2017)

Dynamic and temporal assessment of human dried blood spot MS/MS(ALL) shotgun lipidomics analysis
por: Gao, Fei, et al.
Publicado: (2017)

OMRT-13. Delivery of Ubidecarenone (BPM 31510) to mitochondria effectuates metabolic reprogramming and redox activated apoptosis in Glioblastoma
por: Sarangarajan, Rangaprasad, et al.
Publicado: (2021)

Current Status of Metabolomic Biomarker Discovery: Impact of Study Design and Demographic Characteristics
por: Tolstikov, Vladimir, et al.
Publicado: (2020)

Intragenic Deletions in FLNB Are Part of the Mutational Spectrum Causing Spondylocarpotarsal Synostosis Syndrome
por: Fukushima, Kaya, et al.
Publicado: (2021)

Ethnic Prevalence of Angiotensin-Converting Enzyme Deletion (D) Polymorphism and COVID-19 Risk: Rationale for Use of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers
por: Sarangarajan, Rangaprasad, et al.
Publicado: (2020)

An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer
por: Li, Ji, et al.
Publicado: (2018)

Novel in-frame FLNB deletion causes Larsen syndrome in a three-generation pedigree
por: Hickey, Scott E., et al.
Publicado: (2019)

47 patients with FLNA associated periventricular nodular heterotopia
por: Lange, Max, et al.
Publicado: (2015)

FLNA is implicated in pulmonary neuroendocrine tumors aggressiveness and progression
por: Vitali, Eleonora, et al.
Publicado: (2017)

Three Generations of FLNA-Associated Periventricular Nodular Heterotopia
por: Eisenbiegler, Grace E., et al.
Publicado: (2021)

Normal X-inactivation mosaicism in corneas of heterozygous Flna(Dilp2/+ )female mice--a model of human Filamin A (FLNA) diseases
por: Douvaras, Panagiotis, et al.
Publicado: (2012)

Analysis of KRT1, KRT10, KRT19, TP53 and MMP9 expression in pediatric and adult cholesteatoma
por: Palkó, Enikő, et al.
Publicado: (2018)

Exome sequencing analysis identifies frequent oligogenic involvement and FLNB variants in adolescent idiopathic scoliosis
por: Jiang, Heng, et al.
Publicado: (2020)

High levels of ubidecarenone (oxidized CoQ(10)) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells
por: Sun, Jiaxin, et al.
Publicado: (2020)

PERK interacts with FLNA to regulate ER-PM contact sites
por: van Vliet, Alexander R., et al.
Publicado: (2017)

Role and mechanism of FLNa and UCP2 in the development of cervical cancer
por: Wang, Aihong, et al.
Publicado: (2020)

A novel FLNA variant in a fetus with skeletal dysplasia
por: Oshina, Kyoko, et al.
Publicado: (2022)

Common variants in FLNB/CRTAP, not ARHGEF3 at 3p, are associated with osteoporosis in southern Chinese women
por: Li, G. H. Y., et al.
Publicado: (2009)

Spondylocarpotarsal synostosis syndrome due to a novel loss of function FLNB variant: a case report
por: Yasin, Samina, et al.
Publicado: (2021)

Whole Exome Sequencing in Individuals with Idiopathic Clubfoot Reveals a Recurrent Filamin B (FLNB) Deletion
por: Quiggle, Ashley, et al.
Publicado: (2022)

Hemizygous FLNA variant in West syndrome without periventricular nodular heterotopia
por: Hiromoto, Yoshitaka, et al.
Publicado: (2020)

Heritable FLNA Gene Mutation in a Patient With Thoracic Aortic Aneurysm
por: Siddiqui, Safanah T., et al.
Publicado: (2022)

The clinical and imaging features of FLNA positive and negative periventricular nodular heterotopia
por: Lu, Yan-Ting, et al.
Publicado: (2022)

FLNA-filaminopathy skeletal phenotypes are not due to an osteoblast autonomous loss-of-function
por: Wade, Emma M., et al.
Publicado: (2023)

Identification of a De Novo Heterozygous Missense FLNB Mutation in Lethal Atelosteogenesis Type I by Exome Sequencing
por: Jeon, Ga Won, et al.
Publicado: (2014)

Multi-omic serum biomarkers for prognosis of disease progression in prostate cancer
por: Kiebish, Michael A., et al.
Publicado: (2020)

The expression of FLNA and CLU in PBMCs as a novel screening marker for hepatocellular carcinoma
por: Patarat, Rathasapa, et al.
Publicado: (2021)

Identification of presumed pathogenic KRT3 and KRT12 gene mutations associated with Meesmann corneal dystrophy
por: Chen, Judy L., et al.
Publicado: (2015)

KRT8 and KRT19, associated with EMT, are hypomethylated and overexpressed in lung adenocarcinoma and link to unfavorable prognosis
por: Wang, Wenlong, et al.
Publicado: (2020)

Krt14 and Krt15 differentially regulate regenerative properties and differentiation potential of airway basal cells
por: Ievlev, Vitaly, et al.
Publicado: (2023)

The role of KRT17 in colorectal cancer
por: Ujiie, Daisuke, et al.
Publicado: (2021)

A KRT6A and a Novel KRT16 Gene Mutations in Chinese Patients with Pachyonychia Congenita
por: Gong, Li, et al.
Publicado: (2021)

Integrity of the corpus callosum in patients with periventricular nodular heterotopia related epilepsy by FLNA mutation
por: Liu, Wenyu, et al.
Publicado: (2017)

Terminal osseous dysplasia with pigmentary defects and cardiomyopathy caused by a novel FLNA variant
por: Rumping, Lynne, et al.
Publicado: (2021)

TRIP13/FLNA Complex Promotes Tumor Progression and Is Associated with Unfavorable Outcomes in Melanoma
por: Lu, Wang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j8vvgk4isf1c375va383uik2f1