Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy

Primary mediastinal B-cell lymphoma (PMBCL) is a subtype of non-Hodgkin’s lymphoma, which occurs rarely in pregnancy. We present a case of a pregnant 22-year-old female who presented with syncope and dyspnea. Computed tomography (CT) chest showed an anterior mediastinal mass, and its biopsy showed P...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalid, Sidra, Khalid, Aariez, Daw, Hamed, Maroo, Praful
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910010/
https://www.ncbi.nlm.nih.gov/pubmed/29686956
http://dx.doi.org/10.7759/cureus.2215
_version_ 1783315982359461888
author Khalid, Sidra
Khalid, Aariez
Daw, Hamed
Maroo, Praful
author_facet Khalid, Sidra
Khalid, Aariez
Daw, Hamed
Maroo, Praful
author_sort Khalid, Sidra
collection PubMed
description Primary mediastinal B-cell lymphoma (PMBCL) is a subtype of non-Hodgkin’s lymphoma, which occurs rarely in pregnancy. We present a case of a pregnant 22-year-old female who presented with syncope and dyspnea. Computed tomography (CT) chest showed an anterior mediastinal mass, and its biopsy showed PMBCL. Since she was in her second trimester, we decided to treat her with rituximab-cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP). Our case emphasizes the safety of chemotherapy in the second and third trimesters, with good maternal and fetal outcomes.
format Online
Article
Text
id pubmed-5910010
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-59100102018-04-23 Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy Khalid, Sidra Khalid, Aariez Daw, Hamed Maroo, Praful Cureus Cardiology Primary mediastinal B-cell lymphoma (PMBCL) is a subtype of non-Hodgkin’s lymphoma, which occurs rarely in pregnancy. We present a case of a pregnant 22-year-old female who presented with syncope and dyspnea. Computed tomography (CT) chest showed an anterior mediastinal mass, and its biopsy showed PMBCL. Since she was in her second trimester, we decided to treat her with rituximab-cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP). Our case emphasizes the safety of chemotherapy in the second and third trimesters, with good maternal and fetal outcomes. Cureus 2018-02-21 /pmc/articles/PMC5910010/ /pubmed/29686956 http://dx.doi.org/10.7759/cureus.2215 Text en Copyright © 2018, Khalid et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Khalid, Sidra
Khalid, Aariez
Daw, Hamed
Maroo, Praful
Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy
title Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy
title_full Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy
title_fullStr Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy
title_full_unstemmed Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy
title_short Management of Primary Mediastinal B-Cell Lymphoma in Pregnancy
title_sort management of primary mediastinal b-cell lymphoma in pregnancy
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910010/
https://www.ncbi.nlm.nih.gov/pubmed/29686956
http://dx.doi.org/10.7759/cureus.2215
work_keys_str_mv AT khalidsidra managementofprimarymediastinalbcelllymphomainpregnancy
AT khalidaariez managementofprimarymediastinalbcelllymphomainpregnancy
AT dawhamed managementofprimarymediastinalbcelllymphomainpregnancy
AT maroopraful managementofprimarymediastinalbcelllymphomainpregnancy

Ejemplares similares