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Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia
BACKGROUND: Diagnosis of low-grade dysplasia (LGD) is important in the management of ulcerative colitis (UC), but it is often difficult to distinguish LGD from inflammatory regenerative epithelium. The unfolded protein response (UPR) is activated in inflammatory bowel disease and malignancies. We ai...
Autores principales: | Hanaoka, Marie, Ishikawa, Toshiaki, Ishiguro, Megumi, Tokura, Michiyo, Yamauchi, Shinichi, Kikuchi, Akifumi, Uetake, Hiroyuki, Yasuno, Masamichi, Kawano, Tatsuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Japan
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910497/ https://www.ncbi.nlm.nih.gov/pubmed/28884228 http://dx.doi.org/10.1007/s00535-017-1387-1 |
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