Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway

BACKGROUND: Germinal matrix hemorrhage (GMH) is a common neurologic event with high morbidity and mortality in preterm infants. Spleen has been reported to play a critical role in inflammatory responses by regulating peripheral immune cells which contributes to secondary brain injury. METHODS: The c...

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Detalles Bibliográficos
Autores principales: Zhang, Yiting, Ding, Yan, Lu, Tai, Zhang, Yixin, Xu, Ningbo, McBride, Devin W., Tang, Jiping, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910618/
https://www.ncbi.nlm.nih.gov/pubmed/29678206
http://dx.doi.org/10.1186/s12974-018-1155-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910618/
https://www.ncbi.nlm.nih.gov/pubmed/29678206
http://dx.doi.org/10.1186/s12974-018-1155-z

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