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Biliverdin reductase-A attenuated GMH-induced inflammatory response in the spleen by inhibiting toll-like receptor-4 through eNOS/NO pathway
BACKGROUND: Germinal matrix hemorrhage (GMH) is a common neurologic event with high morbidity and mortality in preterm infants. Spleen has been reported to play a critical role in inflammatory responses by regulating peripheral immune cells which contributes to secondary brain injury. METHODS: The c...
Autores principales: | Zhang, Yiting, Ding, Yan, Lu, Tai, Zhang, Yixin, Xu, Ningbo, McBride, Devin W., Tang, Jiping, Zhang, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910618/ https://www.ncbi.nlm.nih.gov/pubmed/29678206 http://dx.doi.org/10.1186/s12974-018-1155-z |
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