Systemic Inflammatory Response Syndrome in Surgical Patients

OBJECTIVE: To determine the incidence of systemic inflammatory response of the organism in surgical patients and its impact on the outcome of treatment. METHODS: A prospective study was conducted on 60 patients undergoing abdominal surgical procedures, between January 2014 and December 2015 in the Surgery Clinic at the University Clinical Center Tuzla. Two groups of thirty were formed by the method of consecutive sampling. The first group consisted of subjects who were prepared for elective abdominal surgery (laparoscopic cholecystectomy), and the second group subjects underwent an emergency surgery due to acute abdomen (laparoscopic cholecystectomy). RESULTS: The body temperature difference was statistically significant between the two investigated groups in all stages (c(2): t(0)=3,486; t(1)=3,098; t(2)=2,453, t: t(0)=-11,210; t(1)=-7,360; t(2)=-4,927, p < 0,05). Non-elective surgery group had a statistical significant difference of the heart rate at all stages (c(2): t(0)=3,873; t(1)=3,357; t(2)=3,227, t: t(0)=-16,524; t(1)=-10,407; t(2)=-9,842, p < 0,05). There is a statistically significant difference in the pCO2 values in all stages between groups (c(2): t(0)=2,582; t(1)=1,678; t(2)=1,162, t: t(0)=4,323; t(1)=2,653; t(2)=2,229, p < 0,05). The SIRS score has a good positive correlation with the length of treatment, while the correlation with the outcome of treatment has no statistical significance. CONCLUSION: Inflammation scores monitoring in surgical patients is important for the surgical treatment success analysis. By modifying the therapy and influencing the inflammatory response, the results of treatment are improved.