An Intervention Target for Myocardial Fibrosis: Autophagy

Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the resea...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Chunmiao, Yang, Yusong, Zhu, Yaping, Lv, Shichao, Zhang, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911341/
https://www.ncbi.nlm.nih.gov/pubmed/29850542
http://dx.doi.org/10.1155/2018/6215916
_version_ 1783316196541595648
author Lu, Chunmiao
Yang, Yusong
Zhu, Yaping
Lv, Shichao
Zhang, Junping
author_facet Lu, Chunmiao
Yang, Yusong
Zhu, Yaping
Lv, Shichao
Zhang, Junping
author_sort Lu, Chunmiao
collection PubMed
description Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the researchers have also become cumulatively aware of the specified association between autophagy and MF. This review highlights the role of autophagy in MF and the potential effects through the administration of medicine.
format Online
Article
Text
id pubmed-5911341
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-59113412018-05-30 An Intervention Target for Myocardial Fibrosis: Autophagy Lu, Chunmiao Yang, Yusong Zhu, Yaping Lv, Shichao Zhang, Junping Biomed Res Int Review Article Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the researchers have also become cumulatively aware of the specified association between autophagy and MF. This review highlights the role of autophagy in MF and the potential effects through the administration of medicine. Hindawi 2018-04-02 /pmc/articles/PMC5911341/ /pubmed/29850542 http://dx.doi.org/10.1155/2018/6215916 Text en Copyright © 2018 Chunmiao Lu et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Lu, Chunmiao
Yang, Yusong
Zhu, Yaping
Lv, Shichao
Zhang, Junping
An Intervention Target for Myocardial Fibrosis: Autophagy
title An Intervention Target for Myocardial Fibrosis: Autophagy
title_full An Intervention Target for Myocardial Fibrosis: Autophagy
title_fullStr An Intervention Target for Myocardial Fibrosis: Autophagy
title_full_unstemmed An Intervention Target for Myocardial Fibrosis: Autophagy
title_short An Intervention Target for Myocardial Fibrosis: Autophagy
title_sort intervention target for myocardial fibrosis: autophagy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911341/
https://www.ncbi.nlm.nih.gov/pubmed/29850542
http://dx.doi.org/10.1155/2018/6215916
work_keys_str_mv AT luchunmiao aninterventiontargetformyocardialfibrosisautophagy
AT yangyusong aninterventiontargetformyocardialfibrosisautophagy
AT zhuyaping aninterventiontargetformyocardialfibrosisautophagy
AT lvshichao aninterventiontargetformyocardialfibrosisautophagy
AT zhangjunping aninterventiontargetformyocardialfibrosisautophagy
AT luchunmiao interventiontargetformyocardialfibrosisautophagy
AT yangyusong interventiontargetformyocardialfibrosisautophagy
AT zhuyaping interventiontargetformyocardialfibrosisautophagy
AT lvshichao interventiontargetformyocardialfibrosisautophagy
AT zhangjunping interventiontargetformyocardialfibrosisautophagy

Ejemplares similares