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Targeting Beta-Amyloid at the CSF: A New Therapeutic Strategy in Alzheimer’s Disease
Although immunotherapies against the amyloid-β (Aβ) peptide tried so date failed to prove sufficient clinical benefit, Aβ still remains the main target in Alzheimer’s disease (AD). This article aims to show the rationale of a new therapeutic strategy: clearing Aβ from the CSF continuously (the “CSF-...
Autores principales: | Menendez-Gonzalez, Manuel, Padilla-Zambrano, Huber S., Alvarez, Gabriel, Capetillo-Zarate, Estibaliz, Tomas-Zapico, Cristina, Costa, Agustin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911461/ https://www.ncbi.nlm.nih.gov/pubmed/29713273 http://dx.doi.org/10.3389/fnagi.2018.00100 |
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