Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression

Cytosine arabinoside (Ara‐C) is one of the key drugs for the treatment of acute myeloid leukemia. It is also used for consolidation therapy of acute lymphoblastic leukemia (ALL). Ara‐C is a deoxyadenosine analog and is phosphorylated to form cytosine arabinoside triphosphate (Ara‐CTP) as an active f...

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Detalles Bibliográficos
Autores principales: Huang, Meixian, Inukai, Takeshi, Miyake, Kunio, Tanaka, Yoichi, Kagami, Keiko, Abe, Masako, Goto, Hiroaki, Minegishi, Masayoshi, Iwamoto, Shotaro, Sugihara, Eiji, Watanabe, Atsushi, Somazu, Shinpei, Shinohara, Tamao, Oshiro, Hiroko, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911575/
https://www.ncbi.nlm.nih.gov/pubmed/29473342
http://dx.doi.org/10.1002/cam4.1323

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