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PARP inhibitor olaparib sensitizes cholangiocarcinoma cells to radiation

Cholangiocarcinoma (CCA) is a highly malignant tumor with resistance to radiotherapy alone. Olaparib, a highly potent poly(ADP‐ribose) polymerase (PARP) inhibitor, has been shown to sensitize many types of tumor to radiotherapy. However, the effect of olaparib, either as monotherapy or as combinatio...

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Detalles Bibliográficos
Autores principales:	Mao, Yize, Huang, Xin, Shuang, Zeyu, Lin, Guohe, Wang, Jun, Duan, Fangting, Chen, Jianlin, Li, Shengping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911590/ https://www.ncbi.nlm.nih.gov/pubmed/29479816 http://dx.doi.org/10.1002/cam4.1318

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