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Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study

BACKGROUND: The “Physical Activity Reference for Health Promotion 2013” provides “fit” reference values for cardiorespiratory fitness (CRF) for good health. The importance of achieving a fit CRF level for several years on the subsequent prevention of type 2 diabetes mellitus (T2DM) remains to be cla...

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Autores principales: Momma, Haruki, Sawada, Susumu S., Sloan, Robert A., Gando, Yuko, Kawakami, Ryoko, Terada, Shin, Miyachi, Motohiko, Kinugawa, Chihiro, Okamoto, Takashi, Tsukamoto, Koji, Huang, Cong, Nagatomi, Ryoichi, Blair, Steven N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Epidemiological Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911673/
https://www.ncbi.nlm.nih.gov/pubmed/29176273
http://dx.doi.org/10.2188/jea.JE20160199
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author Momma, Haruki
Sawada, Susumu S.
Sloan, Robert A.
Gando, Yuko
Kawakami, Ryoko
Terada, Shin
Miyachi, Motohiko
Kinugawa, Chihiro
Okamoto, Takashi
Tsukamoto, Koji
Huang, Cong
Nagatomi, Ryoichi
Blair, Steven N.
author_facet Momma, Haruki
Sawada, Susumu S.
Sloan, Robert A.
Gando, Yuko
Kawakami, Ryoko
Terada, Shin
Miyachi, Motohiko
Kinugawa, Chihiro
Okamoto, Takashi
Tsukamoto, Koji
Huang, Cong
Nagatomi, Ryoichi
Blair, Steven N.
author_sort Momma, Haruki
collection PubMed
description BACKGROUND: The “Physical Activity Reference for Health Promotion 2013” provides “fit” reference values for cardiorespiratory fitness (CRF) for good health. The importance of achieving a fit CRF level for several years on the subsequent prevention of type 2 diabetes mellitus (T2DM) remains to be clarified. METHODS: This cohort study was conducted in 2,235 nondiabetic males aged 21 to 59 years, enrolled in April 1986 through March 1987. We calculated the ratio of the area under the curve (AUC(ratio)) for actual measured values and the AUC for the reference values of CRF in each individual during an 8-year measurement period before the baseline. According to whether they met a fit CRF level or not, participants were categorized into groups based on the AUC(ratio) (Fit(AUC) or Unfit(AUC)) and initial CRF (Fit(initial) or Unfit(initial)), respectively. T2DM was evaluated on health checkups until March 2010. RESULTS: During the follow-up period, 400 men developed T2DM. After adjustment for confounders, as compared with those in the Fit(AUC) group, the hazard ratio (HR) for those in the Unfit(AUC) group was 1.33 (95% confidence interval [CI], 1.06–1.65). A combined analysis with the categories of initial value and AUC(ratio) showed that, compared with the Fit(initial) and Fit(AUC) group, the HRs of Fit(initial) and Unfit(AUC), Unfit(initial) and Fit(AUC), and Unfit(initial) and Unfit(AUC) groups were 1.41 (95% CI, 0.99–2.00), 1.18 (95% CI, 0.81–1.70), and 1.40 (95% CI, 1.08–1.83), respectively. CONCLUSION: Achievement of a fit CRF level established in the Japan physical activity guideline for several years was associated with lower subsequent risk of T2DM.
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spelling pubmed-59116732018-05-05 Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study Momma, Haruki Sawada, Susumu S. Sloan, Robert A. Gando, Yuko Kawakami, Ryoko Terada, Shin Miyachi, Motohiko Kinugawa, Chihiro Okamoto, Takashi Tsukamoto, Koji Huang, Cong Nagatomi, Ryoichi Blair, Steven N. J Epidemiol Original Article BACKGROUND: The “Physical Activity Reference for Health Promotion 2013” provides “fit” reference values for cardiorespiratory fitness (CRF) for good health. The importance of achieving a fit CRF level for several years on the subsequent prevention of type 2 diabetes mellitus (T2DM) remains to be clarified. METHODS: This cohort study was conducted in 2,235 nondiabetic males aged 21 to 59 years, enrolled in April 1986 through March 1987. We calculated the ratio of the area under the curve (AUC(ratio)) for actual measured values and the AUC for the reference values of CRF in each individual during an 8-year measurement period before the baseline. According to whether they met a fit CRF level or not, participants were categorized into groups based on the AUC(ratio) (Fit(AUC) or Unfit(AUC)) and initial CRF (Fit(initial) or Unfit(initial)), respectively. T2DM was evaluated on health checkups until March 2010. RESULTS: During the follow-up period, 400 men developed T2DM. After adjustment for confounders, as compared with those in the Fit(AUC) group, the hazard ratio (HR) for those in the Unfit(AUC) group was 1.33 (95% confidence interval [CI], 1.06–1.65). A combined analysis with the categories of initial value and AUC(ratio) showed that, compared with the Fit(initial) and Fit(AUC) group, the HRs of Fit(initial) and Unfit(AUC), Unfit(initial) and Fit(AUC), and Unfit(initial) and Unfit(AUC) groups were 1.41 (95% CI, 0.99–2.00), 1.18 (95% CI, 0.81–1.70), and 1.40 (95% CI, 1.08–1.83), respectively. CONCLUSION: Achievement of a fit CRF level established in the Japan physical activity guideline for several years was associated with lower subsequent risk of T2DM. Japan Epidemiological Association 2018-05-05 /pmc/articles/PMC5911673/ /pubmed/29176273 http://dx.doi.org/10.2188/jea.JE20160199 Text en © 2017 Haruki Momma et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Momma, Haruki
Sawada, Susumu S.
Sloan, Robert A.
Gando, Yuko
Kawakami, Ryoko
Terada, Shin
Miyachi, Motohiko
Kinugawa, Chihiro
Okamoto, Takashi
Tsukamoto, Koji
Huang, Cong
Nagatomi, Ryoichi
Blair, Steven N.
Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study
title Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study
title_full Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study
title_fullStr Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study
title_full_unstemmed Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study
title_short Importance of Achieving a “Fit” Cardiorespiratory Fitness Level for Several Years on the Incidence of Type 2 Diabetes Mellitus: A Japanese Cohort Study
title_sort importance of achieving a “fit” cardiorespiratory fitness level for several years on the incidence of type 2 diabetes mellitus: a japanese cohort study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911673/
https://www.ncbi.nlm.nih.gov/pubmed/29176273
http://dx.doi.org/10.2188/jea.JE20160199
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