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Sequence-dependent attack on peptides by photoactivated platinum anticancer complexes
Octahedral platinum(iv) complexes such as trans,trans,trans-[Pt(N(3))(2)(OH)(2)(pyridine)(2)] (1) are stable in the dark, but potently cytotoxic to a range of cancer cells when activated by UVA or visible light, and active in vivo. Photoactivation causes the reduction of the complex and leads to the...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911824/ https://www.ncbi.nlm.nih.gov/pubmed/29732057 http://dx.doi.org/10.1039/c7sc05135b |