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Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen

Lipoarabinomannan (LAM), the major antigenic glycolipid of Mycobacterium tuberculosis, is an important immunodiagnostic target for detecting tuberculosis (TB) infection in HIV-1–coinfected patients, and is believed to mediate a number of functions that promote infection and disease development. To p...

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Detalles Bibliográficos
Autores principales:	Choudhary, Alok, Patel, Deendayal, Honnen, William, Lai, Zhong, Prattipati, Raja Sekhar, Zheng, Ruixiang Blake, Hsueh, Ying-Chao, Gennaro, Maria Laura, Lardizabal, Alfred, Restrepo, Blanca I., Garcia-Viveros, Moncerrato, Joe, Maju, Bai, Yu, Shen, Ke, Sahloul, Kamar, Spencer, John S., Chatterjee, Delphi, Broger, Tobias, Lowary, Todd L., Pinter, Abraham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2018
Materias:	Antigen Recognition and Responses
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911930/ https://www.ncbi.nlm.nih.gov/pubmed/29610143 http://dx.doi.org/10.4049/jimmunol.1701673

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