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Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen
Lipoarabinomannan (LAM), the major antigenic glycolipid of Mycobacterium tuberculosis, is an important immunodiagnostic target for detecting tuberculosis (TB) infection in HIV-1–coinfected patients, and is believed to mediate a number of functions that promote infection and disease development. To p...
Autores principales: | Choudhary, Alok, Patel, Deendayal, Honnen, William, Lai, Zhong, Prattipati, Raja Sekhar, Zheng, Ruixiang Blake, Hsueh, Ying-Chao, Gennaro, Maria Laura, Lardizabal, Alfred, Restrepo, Blanca I., Garcia-Viveros, Moncerrato, Joe, Maju, Bai, Yu, Shen, Ke, Sahloul, Kamar, Spencer, John S., Chatterjee, Delphi, Broger, Tobias, Lowary, Todd L., Pinter, Abraham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911930/ https://www.ncbi.nlm.nih.gov/pubmed/29610143 http://dx.doi.org/10.4049/jimmunol.1701673 |
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