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Transcriptional Repression and Protein Degradation of the Ca(2+)-Activated K(+) Channel K(Ca)1.1 by Androgen Receptor Inhibition in Human Breast Cancer Cells

The large-conductance Ca(2+)-activated K(+) channel K(Ca)1.1 plays an important role in the promotion of breast cancer cell proliferation and metastasis. The androgen receptor (AR) is proposed as a therapeutic target for AR-positive advanced triple-negative breast cancer. We herein investigated the...

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Detalles Bibliográficos
Autores principales:	Khatun, Anowara, Shimozawa, Motoki, Kito, Hiroaki, Kawaguchi, Mayu, Fujimoto, Mayu, Ri, Moe, Kajikuri, Junko, Niwa, Satomi, Fujii, Masanori, Ohya, Susumu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911984/ https://www.ncbi.nlm.nih.gov/pubmed/29713287 http://dx.doi.org/10.3389/fphys.2018.00312

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