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Inhibitory Effects of Simvastatin on Oxidized Low-Density Lipoprotein-Induced Endoplasmic Reticulum Stress and Apoptosis in Vascular Endothelial Cells

BACKGROUND: Oxidized low-density lipoprotein (ox-LDL)-induced oxidative stress and endothelial apoptosis are essential for atherosclerosis. Our previous study has shown that ox-LDL-induced apoptosis is mediated by the protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic translation...

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Detalles Bibliográficos
Autores principales:	Zhang, Guo-Qiang, Tao, Yong-Kang, Bai, Yong-Ping, Yan, Sheng-Tao, Zhao, Shui-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912062/ https://www.ncbi.nlm.nih.gov/pubmed/29664056 http://dx.doi.org/10.4103/0366-6999.229891

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