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The Novel Small Molecule STK899704 Promotes Senescence of the Human A549 NSCLC Cells by Inducing DNA Damage Responses and Cell Cycle Arrest

The novel synthetic compound designated STK899704 (PubChem CID: 5455708) suppresses the proliferation of a broad range of cancer cell types. However, the details of its effect on lung cancer cells are unclear. We investigated the precise anticancer effect of STK899704 on senescence and growth arrest...

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Detalles Bibliográficos
Autores principales:	Park, Chan-Woo, Bak, Yesol, Kim, Min-Je, Srinivasrao, Ganipisetti, Hwang, Joonsung, Sung, Nak K., Kim, Bo Yeon, Yu, Jae-Hyuk, Hong, Jin Tae, Yoon, Do-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912185/ https://www.ncbi.nlm.nih.gov/pubmed/29713275 http://dx.doi.org/10.3389/fphar.2018.00163

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