Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8

Cancer cells release extracellular vesicles (EVs) that contain functional biomolecules such as RNA and proteins. EVs are transferred to recipient cancer cells and can promote tumour progression and therapy resistance. Through RNAi screening, we identified a novel EV uptake mechanism involving a trip...

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Detalles Bibliográficos
Autores principales: Berenguer, Jordi, Lagerweij, Tonny, Zhao, Xi Wen, Dusoswa, Sophie, van der Stoop, Petra, Westerman, Bart, de Gooijer, Mark C., Zoetemelk, Marloes, Zomer, Anoek, Crommentuijn, Matheus H. W., Wedekind, Laurine E., López-López, Àlan, Giovanazzi, Alberta, Bruch-Oms, Marina, van der Meulen-Muileman, Ida H., Reijmers, Rogier M., van Kuppevelt, Toin H., García-Vallejo, Juan-Jesús, van Kooyk, Yvette, Tannous, Bakhos A., Wesseling, Pieter, Koppers-Lalic, Danijela, Vandertop, W. Peter, Noske, David P., van Beusechem, Victor W., van Rheenen, Jacco, Pegtel, D. Michiel, van Tellingen, Olaf, Wurdinger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912193/
https://www.ncbi.nlm.nih.gov/pubmed/29696074
http://dx.doi.org/10.1080/20013078.2018.1446660

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