Cargando…

The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure

PURPOSE: The aim of this study was to evaluate the impact of exposure to biomass smoke vs cigarette smoke on serum inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure (CRF). PATIENTS AND METHODS: A total of 106 patients with CRF divided into age and ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Ocakli, Birsen, Acarturk, Eylem, Aksoy, Emine, Gungor, Sinem, Ciyiltepe, Fulya, Oztas, Selahattin, Ozmen, Ipek, Agca, Meltem Coban, Salturk, Cuneyt, Adiguzel, Nalan, Karakurt, Zuhal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912365/
https://www.ncbi.nlm.nih.gov/pubmed/29713159
http://dx.doi.org/10.2147/COPD.S162658
_version_ 1783316367586361344
author Ocakli, Birsen
Acarturk, Eylem
Aksoy, Emine
Gungor, Sinem
Ciyiltepe, Fulya
Oztas, Selahattin
Ozmen, Ipek
Agca, Meltem Coban
Salturk, Cuneyt
Adiguzel, Nalan
Karakurt, Zuhal
author_facet Ocakli, Birsen
Acarturk, Eylem
Aksoy, Emine
Gungor, Sinem
Ciyiltepe, Fulya
Oztas, Selahattin
Ozmen, Ipek
Agca, Meltem Coban
Salturk, Cuneyt
Adiguzel, Nalan
Karakurt, Zuhal
author_sort Ocakli, Birsen
collection PubMed
description PURPOSE: The aim of this study was to evaluate the impact of exposure to biomass smoke vs cigarette smoke on serum inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure (CRF). PATIENTS AND METHODS: A total of 106 patients with CRF divided into age and gender-matched groups of cigarette-smoke exposure (n=55, mean [SD] age: 71.0 [12.0] years, 92.7% were females) and biomass smoke exposure (n=51, mean [SD] age: 73.0 [11.0] years, 94.1% were females) were included in this retrospective study. Data on patient demographics (age and gender), inflammatory markers, including neutrophil-to-lymphocyte ratio, C-reactive protein, platelet/mean platelet volume ratio, arterial blood gas analysis, and pulmonary function test findings, including forced expiratory volume in 1 second (FEV(1)), forced vital capacity (FVC), and FEV(1)/FVC were obtained from medical records. RESULTS: Carbon dioxide partial pressure levels were significantly higher in the biomass smoke exposure than in the cigarette smoke exposure group (mean [SD] 51.0 [8.0] vs 47.0 [8.0] mmHg, p=0.026, respectively). Spirometry revealed similarly low levels for FEV(1) (%) (38.0 [16.0] vs 40.0 [12.0]%) and FVC (%) (45.0 [19.0] vs 39.0 [19.0]%) in cigarette-smoke and biomass smoke exposure groups, whereas biomass smoke exposure was associated with significantly higher FEV(1)/FVC (75.0 [14.0] vs 58.0 [12.0]%, p=0.001), lower FVC (mL) (mean [SD] 744.0 [410.0] vs 1,063.0 [592.0] mL, p=0.035) and lower percentage of patients with FEV(1)/FVC <70% (36.8% vs 82.0%, p<0.001) than cigarette smoke exposure. CONCLUSION: Our findings indicate similarly increased inflammatory markers and abnormally low pulmonary function test findings in both biomass smoke exposure and cigarette smoke exposure groups, emphasizing the adverse effects of biomass smoke exposure on lungs to be as significant as cigarette smoke exposure. Association of biomass smoke exposure with higher likelihood of FEV(1)/FVC ratio of >70% and more prominent loss of vital capacity than cigarette smoke exposure seems to indicate the likelihood of at least 18 years of biomass exposure to be sufficiently high to be responsible for both obstructive and restrictive pulmonary diseases.
format Online
Article
Text
id pubmed-5912365
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-59123652018-04-30 The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure Ocakli, Birsen Acarturk, Eylem Aksoy, Emine Gungor, Sinem Ciyiltepe, Fulya Oztas, Selahattin Ozmen, Ipek Agca, Meltem Coban Salturk, Cuneyt Adiguzel, Nalan Karakurt, Zuhal Int J Chron Obstruct Pulmon Dis Original Research PURPOSE: The aim of this study was to evaluate the impact of exposure to biomass smoke vs cigarette smoke on serum inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure (CRF). PATIENTS AND METHODS: A total of 106 patients with CRF divided into age and gender-matched groups of cigarette-smoke exposure (n=55, mean [SD] age: 71.0 [12.0] years, 92.7% were females) and biomass smoke exposure (n=51, mean [SD] age: 73.0 [11.0] years, 94.1% were females) were included in this retrospective study. Data on patient demographics (age and gender), inflammatory markers, including neutrophil-to-lymphocyte ratio, C-reactive protein, platelet/mean platelet volume ratio, arterial blood gas analysis, and pulmonary function test findings, including forced expiratory volume in 1 second (FEV(1)), forced vital capacity (FVC), and FEV(1)/FVC were obtained from medical records. RESULTS: Carbon dioxide partial pressure levels were significantly higher in the biomass smoke exposure than in the cigarette smoke exposure group (mean [SD] 51.0 [8.0] vs 47.0 [8.0] mmHg, p=0.026, respectively). Spirometry revealed similarly low levels for FEV(1) (%) (38.0 [16.0] vs 40.0 [12.0]%) and FVC (%) (45.0 [19.0] vs 39.0 [19.0]%) in cigarette-smoke and biomass smoke exposure groups, whereas biomass smoke exposure was associated with significantly higher FEV(1)/FVC (75.0 [14.0] vs 58.0 [12.0]%, p=0.001), lower FVC (mL) (mean [SD] 744.0 [410.0] vs 1,063.0 [592.0] mL, p=0.035) and lower percentage of patients with FEV(1)/FVC <70% (36.8% vs 82.0%, p<0.001) than cigarette smoke exposure. CONCLUSION: Our findings indicate similarly increased inflammatory markers and abnormally low pulmonary function test findings in both biomass smoke exposure and cigarette smoke exposure groups, emphasizing the adverse effects of biomass smoke exposure on lungs to be as significant as cigarette smoke exposure. Association of biomass smoke exposure with higher likelihood of FEV(1)/FVC ratio of >70% and more prominent loss of vital capacity than cigarette smoke exposure seems to indicate the likelihood of at least 18 years of biomass exposure to be sufficiently high to be responsible for both obstructive and restrictive pulmonary diseases. Dove Medical Press 2018-04-18 /pmc/articles/PMC5912365/ /pubmed/29713159 http://dx.doi.org/10.2147/COPD.S162658 Text en © 2018 Ocakli et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Ocakli, Birsen
Acarturk, Eylem
Aksoy, Emine
Gungor, Sinem
Ciyiltepe, Fulya
Oztas, Selahattin
Ozmen, Ipek
Agca, Meltem Coban
Salturk, Cuneyt
Adiguzel, Nalan
Karakurt, Zuhal
The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
title The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
title_full The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
title_fullStr The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
title_full_unstemmed The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
title_short The impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
title_sort impact of exposure to biomass smoke versus cigarette smoke on inflammatory markers and pulmonary function parameters in patients with chronic respiratory failure
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912365/
https://www.ncbi.nlm.nih.gov/pubmed/29713159
http://dx.doi.org/10.2147/COPD.S162658
work_keys_str_mv AT ocaklibirsen theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT acarturkeylem theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT aksoyemine theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT gungorsinem theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT ciyiltepefulya theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT oztasselahattin theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT ozmenipek theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT agcameltemcoban theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT salturkcuneyt theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT adiguzelnalan theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT karakurtzuhal theimpactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT ocaklibirsen impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT acarturkeylem impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT aksoyemine impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT gungorsinem impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT ciyiltepefulya impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT oztasselahattin impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT ozmenipek impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT agcameltemcoban impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT salturkcuneyt impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT adiguzelnalan impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure
AT karakurtzuhal impactofexposuretobiomasssmokeversuscigarettesmokeoninflammatorymarkersandpulmonaryfunctionparametersinpatientswithchronicrespiratoryfailure