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Tandem riboswitches form a natural Boolean logic gate to control purine metabolism in bacteria

Gene control systems sometimes interpret multiple signals to set the expression levels of the genes they regulate. In rare instances, ligand-binding riboswitch aptamers form tandem arrangements to approximate the function of specific two-input Boolean logic gates. Here, we report the discovery of ri...

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Detalles Bibliográficos
Autores principales: Sherlock, Madeline E, Sudarsan, Narasimhan, Stav, Shira, Breaker, Ronald R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912903/
https://www.ncbi.nlm.nih.gov/pubmed/29504937
http://dx.doi.org/10.7554/eLife.33908