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Language recovery after epilepsy surgery of the Broca's area

Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, pa...

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Detalles Bibliográficos
Autores principales: Mnatsakanyan, Lilit, Vadera, Sumeet, Ingalls, Christopher W., Zheng, Jie, Sazgar, Mona, Hsu, Frank P., Lin, Jack J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913035/
https://www.ncbi.nlm.nih.gov/pubmed/29692970
http://dx.doi.org/10.1016/j.ebcr.2017.06.002
Descripción
Sumario:Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, patients are excluded from surgery. We present a patient with drug-resistant frontal lobe epilepsy who underwent successful surgery with resection of Broca's area, primarily involving the pars triangularis (BA 45). We report transient expressive aphasia followed by recovery of speech. This case provides new insights into adult neuroplasticity of the language network.