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Language recovery after epilepsy surgery of the Broca's area

Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, pa...

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Detalles Bibliográficos
Autores principales: Mnatsakanyan, Lilit, Vadera, Sumeet, Ingalls, Christopher W., Zheng, Jie, Sazgar, Mona, Hsu, Frank P., Lin, Jack J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913035/
https://www.ncbi.nlm.nih.gov/pubmed/29692970
http://dx.doi.org/10.1016/j.ebcr.2017.06.002
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author Mnatsakanyan, Lilit
Vadera, Sumeet
Ingalls, Christopher W.
Zheng, Jie
Sazgar, Mona
Hsu, Frank P.
Lin, Jack J.
author_facet Mnatsakanyan, Lilit
Vadera, Sumeet
Ingalls, Christopher W.
Zheng, Jie
Sazgar, Mona
Hsu, Frank P.
Lin, Jack J.
author_sort Mnatsakanyan, Lilit
collection PubMed
description Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, patients are excluded from surgery. We present a patient with drug-resistant frontal lobe epilepsy who underwent successful surgery with resection of Broca's area, primarily involving the pars triangularis (BA 45). We report transient expressive aphasia followed by recovery of speech. This case provides new insights into adult neuroplasticity of the language network.
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spelling pubmed-59130352018-04-24 Language recovery after epilepsy surgery of the Broca's area Mnatsakanyan, Lilit Vadera, Sumeet Ingalls, Christopher W. Zheng, Jie Sazgar, Mona Hsu, Frank P. Lin, Jack J. Epilepsy Behav Case Rep Article Epilepsy surgery is indicated in select patients with drug-resistant focal epilepsy. Seizure freedom or significant reduction of seizure burden without risking new neurological deficits is the expected goal of epilepsy surgery. Typically, when the seizure onset zone overlaps with eloquent cortex, patients are excluded from surgery. We present a patient with drug-resistant frontal lobe epilepsy who underwent successful surgery with resection of Broca's area, primarily involving the pars triangularis (BA 45). We report transient expressive aphasia followed by recovery of speech. This case provides new insights into adult neuroplasticity of the language network. Elsevier 2017-06-17 /pmc/articles/PMC5913035/ /pubmed/29692970 http://dx.doi.org/10.1016/j.ebcr.2017.06.002 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Mnatsakanyan, Lilit
Vadera, Sumeet
Ingalls, Christopher W.
Zheng, Jie
Sazgar, Mona
Hsu, Frank P.
Lin, Jack J.
Language recovery after epilepsy surgery of the Broca's area
title Language recovery after epilepsy surgery of the Broca's area
title_full Language recovery after epilepsy surgery of the Broca's area
title_fullStr Language recovery after epilepsy surgery of the Broca's area
title_full_unstemmed Language recovery after epilepsy surgery of the Broca's area
title_short Language recovery after epilepsy surgery of the Broca's area
title_sort language recovery after epilepsy surgery of the broca's area
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913035/
https://www.ncbi.nlm.nih.gov/pubmed/29692970
http://dx.doi.org/10.1016/j.ebcr.2017.06.002
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