Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009

A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (1–6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The...

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Autores principales: Chen, Rong, Tang, Jian-Wei, Li, Xing-Ren, Liu, Miao, Ding, Wen-Ping, Zhou, Yuan-Fei, Wang, Wei-Guang, Du, Xue, Sun, Han-Dong, Puno, Pema-Tenzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913051/
https://www.ncbi.nlm.nih.gov/pubmed/29556983
http://dx.doi.org/10.1007/s13659-018-0158-x
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author Chen, Rong
Tang, Jian-Wei
Li, Xing-Ren
Liu, Miao
Ding, Wen-Ping
Zhou, Yuan-Fei
Wang, Wei-Guang
Du, Xue
Sun, Han-Dong
Puno, Pema-Tenzin
author_facet Chen, Rong
Tang, Jian-Wei
Li, Xing-Ren
Liu, Miao
Ding, Wen-Ping
Zhou, Yuan-Fei
Wang, Wei-Guang
Du, Xue
Sun, Han-Dong
Puno, Pema-Tenzin
author_sort Chen, Rong
collection PubMed
description A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (1–6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 1–8 were tested for their cytotoxic activity against five human tumor cell lines. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0158-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-59130512018-04-30 Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009 Chen, Rong Tang, Jian-Wei Li, Xing-Ren Liu, Miao Ding, Wen-Ping Zhou, Yuan-Fei Wang, Wei-Guang Du, Xue Sun, Han-Dong Puno, Pema-Tenzin Nat Prod Bioprospect Original Article A detailed chemical investigation of the secondary metabolites produced by the endophytic fungus Xylaria sp. isolated from the stems of Isodon sculponeatus afforded six new compounds, xylariahgins A–F (1–6), two new natural products (7 and 8), along with two known compounds (9 and 10) (Fig. 1). The structures of all compounds were unambiguously established by analyzing their spectroscopic data or referring to pertinent literature. Compounds 1–8 were tested for their cytotoxic activity against five human tumor cell lines. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13659-018-0158-x) contains supplementary material, which is available to authorized users. Springer Singapore 2018-03-20 /pmc/articles/PMC5913051/ /pubmed/29556983 http://dx.doi.org/10.1007/s13659-018-0158-x Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Chen, Rong
Tang, Jian-Wei
Li, Xing-Ren
Liu, Miao
Ding, Wen-Ping
Zhou, Yuan-Fei
Wang, Wei-Guang
Du, Xue
Sun, Han-Dong
Puno, Pema-Tenzin
Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_full Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_fullStr Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_full_unstemmed Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_short Secondary Metabolites from the Endophytic Fungus Xylaria sp. hg1009
title_sort secondary metabolites from the endophytic fungus xylaria sp. hg1009
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913051/
https://www.ncbi.nlm.nih.gov/pubmed/29556983
http://dx.doi.org/10.1007/s13659-018-0158-x
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