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The IL-33-PIN1-IRAK-M axis is critical for type 2 immunity in IL-33-induced allergic airway inflammation
Interleukin 33 (IL-33) is among the earliest-released cytokines in response to allergens that orchestrate type 2 immunity. The prolyl cis-trans isomerase PIN1 is known to induce cytokines for eosinophil survival and activation by stabilizing cytokines mRNAs, but the function of PIN1 in upstream sign...
Autores principales: | Nechama, Morris, Kwon, Jeahoo, Wei, Shuo, Tun-Kyi, Adrian, Welner, Robert S., Ben-Dov, Iddo Z., Arredouani, Mohamed S., Asara, John M., Chen, Chun-Hau, Tsai, Cheng-Yu, Nelson, Kyle F., Kobayashi, Koichi S, Israel, Elliot, Zhou, Xiao Zhen, Nicholson, Linda K., Lu, Kun Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913134/ https://www.ncbi.nlm.nih.gov/pubmed/29686383 http://dx.doi.org/10.1038/s41467-018-03886-6 |
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