Mitochondrial DNA induces Foley catheter related bladder inflammation via Toll-like receptor 9 activation

Bladder instrumentation engages the innate immune system via neutrophil activation, promoting inflammation and pain. Elevated levels of mitochondrial DNA (mtDNA) have been associated with tissue damage and organ dysfunction. We hypothesized that local bladder trauma induced by a Foley catheter (FC)...

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Detalles Bibliográficos
Autores principales: Puyo, Carlos A., Earhart, Alexander, Staten, Nicholas, Huang, Yuan, Desai, Alana, Lai, Henry, Venkatesh, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913242/
https://www.ncbi.nlm.nih.gov/pubmed/29686303
http://dx.doi.org/10.1038/s41598-018-24818-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913242/
https://www.ncbi.nlm.nih.gov/pubmed/29686303
http://dx.doi.org/10.1038/s41598-018-24818-w

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