Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance

The existence of rare cancer cells that sporadically acquire drug-tolerance through epigenetic mechanisms is proposed as one mechanism that drives cancer therapy failure. Here we provide evidence that specific microenvironments impose non-sporadic expression of proteins related to epithelial plastic...

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Detalles Bibliográficos
Autores principales: Jokela, Tiina A., Engelsen, Agnete S. T., Rybicka, Agata, Pelissier Vatter, Fanny A., Garbe, James C., Miyano, Masaru, Tiron, Crina, Ferariu, Dan, Akslen, Lars A., Stampfer, Martha R., Lorens, James B., LaBarge, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913284/
https://www.ncbi.nlm.nih.gov/pubmed/29719832
http://dx.doi.org/10.3389/fcell.2018.00041

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