Cargando…

Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of CFHR4

Recent research has elucidated circulating levels of almost all factor H-related (FHR) proteins. Some of these proteins are hypothesized to act as antagonists of the important complement regulator factor H (FH), fine-tuning complement regulation on human surfaces. For the CFHR4 splice variants FHR-4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pouw, Richard B., Brouwer, Mieke C., van Beek, Anna E., Józsi, Mihály, Wouters, Diana, Kuijpers, Taco W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913293/ https://www.ncbi.nlm.nih.gov/pubmed/29719534 http://dx.doi.org/10.3389/fimmu.2018.00729

Ejemplares similares

High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B
por: Pouw, Richard B., et al.
Publicado: (2018)

Corrigendum: High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3(*)B
por: Pouw, Richard B., et al.
Publicado: (2020)

Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3
por: Pouw, Richard B., et al.
Publicado: (2016)

Deletion of Complement Factor H–Related Genes CFHR1 and CFHR3 Is Associated with Atypical Hemolytic Uremic Syndrome
por: Zipfel, Peter F, et al.
Publicado: (2007)

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma
por: van Beek, Anna E., et al.
Publicado: (2017)

Self-Damage Caused by Dysregulation of the Complement Alternative Pathway: Relevance of the Factor H Protein Family
por: Sánchez-Corral, Pilar, et al.
Publicado: (2018)

Factor H Family Proteins in Complement Evasion of Microorganisms
por: Józsi, Mihály
Publicado: (2017)

Editorial: Updates on the complement system in kidney diseases
por: Bulla, Roberta, et al.
Publicado: (2023)

Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases
por: Schäfer, Nicole, et al.
Publicado: (2016)

Editorial: Function and Dysfunction of Complement Factor H
por: Józsi, Mihály, et al.
Publicado: (2022)

Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration
por: Lorés-Motta, Laura, et al.
Publicado: (2021)

Analysis of Linear Antibody Epitopes on Factor H and CFHR1 Using Sera of Patients with Autoimmune Atypical Hemolytic Uremic Syndrome
por: Trojnár, Eszter, et al.
Publicado: (2017)

Identification of CFHR4 as a Potential Prognosis Biomarker Associated With lmmune Infiltrates in Hepatocellular Carcinoma
por: Yu, Hongjun, et al.
Publicado: (2022)

Human Pentraxin 3 Binds to the Complement Regulator C4b-Binding Protein
por: Braunschweig, Anne, et al.
Publicado: (2011)

Low Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis
por: van Beek, Anna E., et al.
Publicado: (2022)

The High Prevalence of Functional Complement Defects Induced by Chemotherapy
por: Keizer, Mischa P., et al.
Publicado: (2016)

Variation in CFHR3 determines susceptibility to meningococcal disease by controlling factor H concentrations
por: Kumar, Vikrant, et al.
Publicado: (2022)

Autoantibodies against complement factor B in rheumatoid arthritis
por: Matola, Alexandra T., et al.
Publicado: (2023)

Complement Factor H Family Proteins Modulate Monocyte and Neutrophil Granulocyte Functions
por: Kárpáti, Éva, et al.
Publicado: (2021)

CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome
por: Piras, Rossella, et al.
Publicado: (2023)

Regulating complement in the kidney: insights from CFHR5 nephropathy
por: Gale, Daniel P., et al.
Publicado: (2011)

The Murine Factor H-Related Protein FHR-B Promotes Complement Activation
por: Cserhalmi, Marcell, et al.
Publicado: (2017)

Complement factor H contributes to mortality in humans and mice with bacterial meningitis
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2019)

Complement Factor H Levels Associate With Plasmodium falciparum Malaria Susceptibility and Severity
por: van Beek, Anna E, et al.
Publicado: (2018)

Functional Characterization of the Disease-Associated N-Terminal Complement Factor H Mutation W198R
por: Cserhalmi, Marcell, et al.
Publicado: (2017)

Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities
por: Dekkers, Gillian, et al.
Publicado: (2017)

Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi
por: Siegel, Corinna, et al.
Publicado: (2010)

FHR-5 Serum Levels and CFHR5 Genetic Variations in Patients With Immune Complex-Mediated Membranoproliferative Glomerulonephritis and C3-Glomerulopathy
por: Garam, Nóra, et al.
Publicado: (2021)

Identification of CFHR4 associated with poor prognosis of hepatocellular carcinoma
por: Ding, Qinglin, et al.
Publicado: (2022)

Interaction of the Factor H Family Proteins FHR-1 and FHR-5 With DNA and Dead Cells: Implications for the Regulation of Complement Activation and Opsonization
por: Kárpáti, Éva, et al.
Publicado: (2020)

Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes
por: Keizer, Mischa P., et al.
Publicado: (2018)

Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder
por: Uzonyi, Barbara, et al.
Publicado: (2021)

Reference Intervals of Factor H and Factor H-Related Proteins in Healthy Children
por: van Beek, Anna E., et al.
Publicado: (2018)

Efficient complement-mediated clearance of immunosuppressed T cells by macrophages
por: Gankema, Angela A. F., et al.
Publicado: (2023)

Human Factor H-Related Protein 2 (CFHR2) Regulates Complement Activation
por: Eberhardt, Hannes U., et al.
Publicado: (2013)

Pathogenic Neisseria Bind the Complement Protein CFHR5 via Outer Membrane Porins
por: Yee, Wearn-Xin, et al.
Publicado: (2022)

Complement Factor H-Related Proteins FHR1 and FHR5 Interact With Extracellular Matrix Ligands, Reduce Factor H Regulatory Activity and Enhance Complement Activation
por: Papp, Alexandra, et al.
Publicado: (2022)

Determining the Population Frequency of the CFHR3/CFHR1 Deletion at 1q32
por: Holmes, Lucy V., et al.
Publicado: (2013)

Elevated Systemic Pentraxin-3 Is Associated With Complement Consumption in the Acute Phase of Thrombotic Microangiopathies
por: Trojnar, Eszter, et al.
Publicado: (2019)

Associations of CFH Polymorphisms and CFHR1-CFHR3 Deletion with Blood Pressure and Hypertension in Chinese Population
por: Gan, Wei, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_m6ht2i2rc9jv820ma95tvto77v