Cargando…

High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer

Indoleamine 2,3-dioxygenase (IDO), which catalyzes the breakdown of the essential amino acid tryptophan into kynurenine, is understood to have a key role in cancer immunotherapy. IDO has also received more attention because of its non-immune functions including regulating angiogenesis. The purpose o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Lijuan, Zhu, Shanshan, Li, Menghui, Li, Fangxuan, Wei, Feng, Liu, Juntian, Ren, Xiubao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913323/ https://www.ncbi.nlm.nih.gov/pubmed/29719533 http://dx.doi.org/10.3389/fimmu.2018.00724

Ejemplares similares

Indoleamine-2,3-dioxygenase and Interleukin-6 associated with tumor response to neoadjuvant chemotherapy in breast cancer
por: Li, Fangxuan, et al.
Publicado: (2017)

Editorial: Targeting Indoleamine 2,3-dioxygenases and Tryptophan Dioxygenase for Cancer Immunotherapy
por: Brochez, Lieve, et al.
Publicado: (2021)

Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?
por: Mellor, Andrew L., et al.
Publicado: (2017)

Indoleamine 2,3-Dioxygenase 1: A Promising Therapeutic Target in Malignant Tumor
por: Song, Xiaotian, et al.
Publicado: (2021)

The Role of Indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy
por: Hornyák, Lilla, et al.
Publicado: (2018)

Targeting Indoleamine 2,3-Dioxygenase 1: Fighting Cancers via Dormancy Regulation
por: Yang, Chao, et al.
Publicado: (2021)

Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells
por: Sun, Jingyan, et al.
Publicado: (2011)

The role of indoleamine 2,3-dioxygenase 1 in early-onset post-stroke depression
por: Chen, Hengshu, et al.
Publicado: (2023)

Upregulated Expression of Indoleamine 2, 3-Dioxygenase in Primary Breast Cancer Correlates with Increase of Infiltrated Regulatory T Cells In Situ and Lymph Node Metastasis
por: Yu, Jinpu, et al.
Publicado: (2011)

Localization of Indoleamine 2,3-Dioxygenase-1 and Indoleamine 2,3-Dioxygenase-2 at the Human Maternal-Fetal Interface
por: Kudo, Yoshiki, et al.
Publicado: (2020)

What May Constrain the Success of Indoleamine 2,3-Dioxygenase 1 Inhibitors in Cancer Immunotherapy?
por: Eleftheriadis, Theodoros
Publicado: (2018)

Investigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review
por: Wells, Georgia, et al.
Publicado: (2021)

GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer
por: Meng, Yinnan, et al.
Publicado: (2021)

Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults
por: Riazati, Niknaz, et al.
Publicado: (2022)

Interleukin-6 and indoleamine-2,3-dioxygenase as potential adjuvant targets for Papillomavirus-related tumors immunotherapy
por: Pagni, Roberta Liberato, et al.
Publicado: (2022)

Indoleamine 2,3-dioxygenase 1 signaling orchestrates immune tolerance in Echinococcus multilocularis-infected mice
por: Meng, Ru, et al.
Publicado: (2022)

Disease Tolerance Mediated by Phosphorylated Indoleamine-2,3 Dioxygenase Confers Resistance to a Primary Fungal Pathogen
por: de Araújo, Eliseu Frank, et al.
Publicado: (2017)

A Multifaceted Role of Tryptophan Metabolism and Indoleamine 2,3-Dioxygenase Activity in Aspergillus fumigatus–Host Interactions
por: Choera, Tsokyi, et al.
Publicado: (2018)

Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice
por: Forteza, Maria J., et al.
Publicado: (2018)

Indoleamine 2,3-Dioxygenase Cannot Inhibit Chlamydia trachomatis Growth in HL-60 Human Neutrophil Granulocytes
por: Virok, Dezső P., et al.
Publicado: (2021)

Targeting the indoleamine 2,3-dioxygenase pathway in cancer
por: Moon, Yong Wha, et al.
Publicado: (2015)

Computational study on new natural compound inhibitors of indoleamine 2,3-dioxygenase 1
por: Jiang, Shanshan, et al.
Publicado: (2020)

An Expanded Neuroimmunomodulation Axis: sCD83-Indoleamine 2,3-Dioxygenase—Kynurenine Pathway and Updates of Kynurenine Pathway in Neurologic Diseases
por: Bo, Li, et al.
Publicado: (2018)

Indoleamine 2,3-Dioxygenase Expression Pattern in the Tumor Microenvironment Predicts Clinical Outcome in Early Stage Cervical Cancer
por: Heeren, A. Marijne, et al.
Publicado: (2018)

Expression of Indoleamine 2,3-Dioxygenase Induced by IFN-γ and TNF-α as Potential Biomarker of Prostate Cancer Progression
por: Banzola, Irina, et al.
Publicado: (2018)

The Proteasome Inhibitor Bortezomib Controls Indoleamine 2,3-Dioxygenase 1 Breakdown and Restores Immune Regulation in Autoimmune Diabetes
por: Mondanelli, Giada, et al.
Publicado: (2017)

Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0
por: Grobben, Yvonne, et al.
Publicado: (2021)

Forty‐three key gene expressions involved in the effect of indoleamine 2,3‐dioxygenase 1 expression on cancer prognosis may be a potential indoleamine 2,3‐dioxygenase 1 inhibitor biomarker
por: Li, Weirui, et al.
Publicado: (2021)

Indoleamine-2,3-Dioxygenase 1 Deficiency Suppresses Seizures in Epilepsy
por: Deng, Ning, et al.
Publicado: (2021)

The Mechanism of Substrate Inhibition in Human Indoleamine 2,3-Dioxygenase
por: Efimov, Igor, et al.
Publicado: (2012)

Indoleamine-2,3-dioxygenase activity induces neutrophil apoptosis
por: Van der Sluijs, K, et al.
Publicado: (2011)

Indoleamine-2,3-dioxygenase activity in experimental human endotoxemia
por: Padberg, Jan-Sören, et al.
Publicado: (2012)

The role of placental indoleamine 2,3-dioxygenase in human pregnancy
por: Kudo, Yoshiki
Publicado: (2013)

Advances in indoleamine 2,3-dioxygenase 1 medicinal chemistry
por: Coletti, Alice, et al.
Publicado: (2017)

Role of indoleamine 2,3-dioxygenase in pathology of the gastrointestinal tract
por: Acovic, Aleksandar, et al.
Publicado: (2018)

Role of indoleamine 2,3-dioxygenase in testicular immune-privilege
por: Gualdoni, Gisela S., et al.
Publicado: (2019)

Commentary: Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells
por: Maffia, Pasquale, et al.
Publicado: (2017)

Indoleamine 2,3-Dioxygenase 1 Inhibitor-Loaded Nanosheets Enhance CAR-T Cell Function in Esophageal Squamous Cell Carcinoma
por: Shao, Jingwen, et al.
Publicado: (2021)

Hypoxia enhances indoleamine 2,3-dioxygenase production in dendritic cells
por: Song, Xiang, et al.
Publicado: (2018)

Association of Microbial Tryptophan Metabolites and Indoleamine-2,3-Dioxygenase with Immune Activity in Healthy Adults
por: Riazati, Niknaz, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t9j015b60qd3180ul8dpe87feg