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Longitudinal analysis strategies for modelling epigenetic trajectories
BACKGROUND: DNA methylation levels are known to vary over time, and modelling these trajectories is crucial for our understanding of the biological relevance of these changes over time. However, due to the computational cost of fitting multilevel models across the epigenome, most trajectory modellin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913606/ https://www.ncbi.nlm.nih.gov/pubmed/29462323 http://dx.doi.org/10.1093/ije/dyy012 |