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A RecET-assisted CRISPR–Cas9 genome editing in Corynebacterium glutamicum

BACKGROUND: Extensive modification of genome is an efficient manner to regulate the metabolic network for producing target metabolites or non-native products using Corynebacterium glutamicum as a cell factory. Genome editing approaches by means of homologous recombination and counter-selection marke...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Hu, Qitiao, Zhang, Yu, Shi, Ruilin, Chai, Xin, Liu, Zhe, Shang, Xiuling, Zhang, Yun, Wen, Tingyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913818/
https://www.ncbi.nlm.nih.gov/pubmed/29685154
http://dx.doi.org/10.1186/s12934-018-0910-2