Cargando…

Autoregulation and Virulence Control by the Toxin-Antitoxin System SavRS in Staphylococcus aureus

Toxin-antitoxin (TA) systems play diverse physiological roles, such as plasmid maintenance, growth control, and persister cell formation, but their involvement in bacterial pathogenicity remains largely unknown. Here, we have identified a novel type II toxin-antitoxin system, SavRS, and revealed the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Wen, Liu, Banghui, Xue, Lu, Zhu, Zhongliang, Niu, Liwen, Sun, Baolin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Molecular Pathogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913840/ https://www.ncbi.nlm.nih.gov/pubmed/29440365 http://dx.doi.org/10.1128/IAI.00032-18

Ejemplares similares

Bioinformatics and Functional Assessment of Toxin-Antitoxin Systems in Staphylococcus aureus
por: Habib, Gul, et al.
Publicado: (2018)

Toxin-Antitoxin Systems of Staphylococcus aureus
por: Schuster, Christopher F., et al.
Publicado: (2016)

Rsp promotes the transcription of virulence factors in an agr-independent manner in Staphylococcus aureus
por: Liu, Banghui, et al.
Publicado: (2020)

The two paralogous copies of the YoeB–YefM toxin–antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns
por: Xue, Lu, et al.
Publicado: (2021)

The Major Autolysin Atl Regulates the Virulence of Staphylococcus aureus by Controlling the Sorting of LukAB
por: Zheng, Xuhui, et al.
Publicado: (2022)

Distinct oligomeric structures of the YoeB–YefM complex provide insights into the conditional cooperativity of type II toxin–antitoxin system
por: Xue, Lu, et al.
Publicado: (2020)

Structural insights into the PrpTA toxin–antitoxin system in Pseudoalteromonas rubra
por: Wang, Chenchen, et al.
Publicado: (2022)

Structure of the sirtuin‐linked macrodomain SAV0325 from Staphylococcus aureus
por: Appel, C. Denise, et al.
Publicado: (2016)

Bovine Staphylococcus aureus Superantigens Stimulate the Entire T Cell Repertoire of Cattle
por: Wilson, Gillian J., et al.
Publicado: (2018)

A Small Membrane Stabilizing Protein Critical to the Pathogenicity of Staphylococcus aureus
por: Duggan, Seána, et al.
Publicado: (2020)

SarS Is a Repressor of Staphylococcus aureus Bicomponent Pore-Forming Leukocidins
por: Anderson, Exene E., et al.
Publicado: (2023)

Convergent Evolution of Antibiotic Tolerance in Patients with Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia
por: Elgrail, Mitra M., et al.
Publicado: (2022)

Crucial Role for Lipoteichoic Acid Assembly in the Metabolic Versatility and Antibiotic Resistance of Staphylococcus aureus
por: Burtchett, Troy A., et al.
Publicado: (2023)

Autoregulation of bacterial gene expression: lessons from the MazEF toxin–antitoxin system
por: Nikolic, Nela
Publicado: (2018)

Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences
por: Beck, Izaak N., et al.
Publicado: (2020)

The MazEF Toxin-Antitoxin System Alters the β-Lactam Susceptibility of Staphylococcus aureus
por: Schuster, Christopher F., et al.
Publicado: (2015)

Genome mining reveals the prevalence and extensive diversity of toxin–antitoxin systems in Staphylococcus aureus
por: Xu, Jie, et al.
Publicado: (2023)

Characterization of lytic activity of Phage SAvB14 on Staphylococcus aureus variant bovis
por: Horiuk, Yulia, et al.
Publicado: (2020)

HtrA Is Important for Stress Resistance and Virulence in Haemophilus parasuis
por: Zhang, Luhua, et al.
Publicado: (2016)

SpoVG Modulates Cell Aggregation in Staphylococcus aureus by Regulating sasC Expression and Extracellular DNA Release
por: Zhu, Qing, et al.
Publicado: (2020)

Staphylococcus aureus Adapts to Oxidative Stress by Producing H(2)O(2)-Resistant Small-Colony Variants via the SOS Response
por: Painter, Kimberley L., et al.
Publicado: (2015)

Structural and functional studies of SAV0551 from Staphylococcus aureus as a chaperone and glyoxalase III
por: Kim, Hyo Jung, et al.
Publicado: (2017)

Significant variability exists in the cytotoxicity of global methicillin-resistant Staphylococcus aureus lineages
por: Laabei, Maisem, et al.
Publicado: (2021)

A functional menadione biosynthesis pathway is required for capsule production by Staphylococcus aureus
por: Altwiley, Dina, et al.
Publicado: (2021)

The Toxin-Antitoxin MazEF Drives Staphylococcus aureus Biofilm Formation, Antibiotic Tolerance, and Chronic Infection
por: Ma, Dongzhu, et al.
Publicado: (2019)

The SAV1322 gene from Staphylococcus aureus: genomic and proteomic approaches to identification and characterization of gene function
por: Kim, Jung Wook, et al.
Publicado: (2016)

The MpsB protein contributes to both the toxicity and immune evasion capacity of Staphylococcus aureus
por: Douglas, Edward J. A., et al.
Publicado: (2021)

Methylthioadenosine Suppresses Salmonella Virulence
por: Bourgeois, Jeffrey S., et al.
Publicado: (2018)

A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice
por: De la Cruz, Miguel A., et al.
Publicado: (2013)

The Pseudoknot Region of the 5′ Untranslated Region Is a Determinant of Viral Tropism and Virulence of Foot-and-Mouth Disease Virus
por: Zhu, Zixiang, et al.
Publicado: (2019)

YjbH Solubility Controls Spx in Staphylococcus aureus: Implication for MazEF Toxin-Antitoxin System Regulation
por: Panasenko, Olesya O., et al.
Publicado: (2020)

Recruitment of C4b-binding protein is not a complement evasion strategy employed by Staphylococcus aureus
por: Li, Shuxian, et al.
Publicado: (2023)

Structural and mutational analysis of MazE6-operator DNA complex provide insights into autoregulation of toxin-antitoxin systems
por: Kumari, Khushboo, et al.
Publicado: (2022)

Retraction: A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice
Publicado: (2020)

Time Series Transcriptomic Analysis of Bronchoalveolar Lavage Cells from Piglets Infected with Virulent or Low-Virulent Porcine Reproductive and Respiratory Syndrome Virus 1
por: Sánchez-Carvajal, J. M., et al.
Publicado: (2022)

In Vivo Virulence Characterization of Pregnancy-Associated Listeria monocytogenes Infections
por: Morrison, Holly A., et al.
Publicado: (2018)

Functionality and cross-regulation of the four SprG/SprF type I toxin–antitoxin systems in Staphylococcus aureus
por: Riffaud, Camille, et al.
Publicado: (2019)

The N-Terminal Region of Middle East Respiratory Syndrome Coronavirus Accessory Protein 8b Is Essential for Enhanced Virulence of an Attenuated Murine Coronavirus
por: Li, Yuming, et al.
Publicado: (2022)

Tetanus Toxin and Antitoxin
por: McFarland, Joseph, et al.
Publicado: (1899)

Tetanus Toxin and Antitoxin
por: McFarland, Joseph, et al.
Publicado: (1899)

Cannot write session to /tmp/vufind_sessions/sess_oo5v7bcuoqod6ctt72pddsp2um