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First case of AML with rare chromosome translocations: a case report of twins

BACKGROUND: Leukemia is different from solid tumor by harboring genetic rearrangements that predict prognosis and guide treatment strategy. PML-RARA, RUNX1-RUNX1T1, and KMT2A-rearrangement are common genetic rearrangements that drive the development of acute myeloid leukemia (AML). By contrast, rare...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Sun, Yanhua, Sun, Yanli, Meng, Lingbin, Xu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913884/
https://www.ncbi.nlm.nih.gov/pubmed/29688850
http://dx.doi.org/10.1186/s12885-018-4396-4