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Optimization of a Therapeutic Vaccine Candidate by Studying Routes, Immunization Schedules and Antigen Doses in HBsAg-positive Transgenic Mice

Hepatitis B core antigens (HBcAg) and hepatitis B surface antigens (HBsAg) are the main structural antigens of hepatitis B virus (HBV). Both antigens are potent immunogens for experimental animals as well as in acutely infected patients. A novel formulation based on the combination of HBsAg and HBcA...

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Detalles Bibliográficos
Autores principales:	Trujillo, H, Blanco, A, García, D, Freyre, F, Aguiar, J, Lobaina, Y, Aguilar, JC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Jaypee Brothers Medical Publishers 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913899/ https://www.ncbi.nlm.nih.gov/pubmed/29699351 http://dx.doi.org/10.5005/jp-journals-10018-1105

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