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Treatment of pancreatic ductal adenocarcinoma with tumor antigen specific-targeted delivery of paclitaxel loaded PLGA nanoparticles

BACKGROUND: Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe side effects in patients with PDA and does not significantly improve overall survival rate. It is highly desirable to advance th...

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Detalles Bibliográficos
Autores principales: Wu, Shu-ta, Fowler, Anthony J., Garmon, Corey B., Fessler, Adam B., Ogle, Joshua D., Grover, Kajal R., Allen, Bailey C., Williams, Chandra D., Zhou, Ru, Yazdanifar, Mahboubeh, Ogle, Craig A., Mukherjee, Pinku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914049/
https://www.ncbi.nlm.nih.gov/pubmed/29685122
http://dx.doi.org/10.1186/s12885-018-4393-7