miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy

BACKGROUND: Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the first and rate-limiting step in converting tryptophan to kynurenine. Chimeric antigen receptor (CAR) T cells are T cells with recombinant receptors targeting tumor-associated antigens. The Food and Drug Administration has approved CAR T...

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Detalles Bibliográficos
Autores principales: Huang, Qian, Xia, Jiajia, Wang, Lei, Wang, Xu, Ma, Xiaodong, Deng, Qipan, Lu, Yong, Kumar, Munish, Zhou, Zhiyuan, Li, Ling, Zeng, Zhaoyang, Young, Ken H., Yi, Qing, Zhang, Mingzhi, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914051/
https://www.ncbi.nlm.nih.gov/pubmed/29685162
http://dx.doi.org/10.1186/s13045-018-0600-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914051/
https://www.ncbi.nlm.nih.gov/pubmed/29685162
http://dx.doi.org/10.1186/s13045-018-0600-x

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