Oxidative Stress Induces HSP90 Upregulation on the Surface of Primary Human Endothelial Cells: Role of the Antioxidant 7,8-Dihydroxy-4-methylcoumarin in Preventing HSP90 Exposure to the Immune System

We have previously demonstrated that human heat shock protein 90 (HSP90), an intracellular self protein, is the target of cellular and humoral autoimmune responses in patients with carotid atherosclerosis. In this study, we evaluated in vitro whether oxidative stress, a feature of atherosclerotic pl...

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Detalles Bibliográficos
Autores principales: Profumo, Elisabetta, Buttari, Brigitta, Tinaburri, Lavinia, D'Arcangelo, Daniela, Sorice, Maurizio, Capozzi, Antonella, Garofalo, Tina, Facchiano, Antonio, Businaro, Rita, Kumar, Prashant, Singh, Brajendra K., Parmar, Virinder S., Saso, Luciano, Riganò, Rachele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914108/
https://www.ncbi.nlm.nih.gov/pubmed/29849874
http://dx.doi.org/10.1155/2018/2373167

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