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Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery

INTRODUCTION: Ultrafast tracking of anesthesia (UFTA) is practiced routinely, whereas immediate on-table extubation after off-pump coronary artery bypass (OPCAB) grafting surgery has many concerns. The purpose of our study was to evaluate the safety and feasibility of immediate extubation (IE) versu...

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Autores principales: Nagre, Amarja Sachin, Jambures, Nagesh P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914211/
https://www.ncbi.nlm.nih.gov/pubmed/29652272
http://dx.doi.org/10.4103/aca.ACA_135_17
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author Nagre, Amarja Sachin
Jambures, Nagesh P
author_facet Nagre, Amarja Sachin
Jambures, Nagesh P
author_sort Nagre, Amarja Sachin
collection PubMed
description INTRODUCTION: Ultrafast tracking of anesthesia (UFTA) is practiced routinely, whereas immediate on-table extubation after off-pump coronary artery bypass (OPCAB) grafting surgery has many concerns. The purpose of our study was to evaluate the safety and feasibility of immediate extubation (IE) versus UFTA. METHODS: Sixty patients were enrolled who underwent OPCAB surgery. The two groups IE and UFTA had thirty patients each. Inclusion criteria were patients for OPCAB surgery including left main stenosis. Exclusion criteria were patients with Ejection Fraction(EF) <30%, with unstable hemodynamics, on intra-aortic balloon pump (IABP), with renal dysfunction, with associated valvular heart diseases, on inotropes, on temporary pacemaker, with intraoperative conversion to on-pump coronary artery bypass grafting (CABG), who are chronic smokers, and with chronic obstructive pulmonary disease. Statistical analysis was done with Minitab 15 software. Descriptive statistics were summarized as mean, standard deviation, and percentage. Student's t-test was used to determine the significance of normally distributed parametric values. Z-test was used for proportion. Statistical significance was accepted at P < 0.05. RESULTS: OT extubation was found to be safe as no patient had reintubation or respiratory insufficiency. None of the patients in either group had postoperative myocardial infarction, stroke, low cardiac output, mediastinitis, and renal failure. Hypothermia, blood transfusion, atrial fibrillation, and re-exploration did not occur. Intensive Care Unit length of stay was similar in the two groups. Discharge day is statistically significant (P = 0.001), with 5.66 days in the IE group and 6.36 days in the UFTA group. Time spent in the operating room at the end of surgery is statistically significant, with 14.03 min in UFTA group and 33.9 min in IE group. CONCLUSION: IE appears to be safe and effective in OPCAB patients without any major complications. It can be achieved after fulfilling traditional extubation criteria but is confined to highly selective group of patients.
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spelling pubmed-59142112018-05-07 Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery Nagre, Amarja Sachin Jambures, Nagesh P Ann Card Anaesth Original Article INTRODUCTION: Ultrafast tracking of anesthesia (UFTA) is practiced routinely, whereas immediate on-table extubation after off-pump coronary artery bypass (OPCAB) grafting surgery has many concerns. The purpose of our study was to evaluate the safety and feasibility of immediate extubation (IE) versus UFTA. METHODS: Sixty patients were enrolled who underwent OPCAB surgery. The two groups IE and UFTA had thirty patients each. Inclusion criteria were patients for OPCAB surgery including left main stenosis. Exclusion criteria were patients with Ejection Fraction(EF) <30%, with unstable hemodynamics, on intra-aortic balloon pump (IABP), with renal dysfunction, with associated valvular heart diseases, on inotropes, on temporary pacemaker, with intraoperative conversion to on-pump coronary artery bypass grafting (CABG), who are chronic smokers, and with chronic obstructive pulmonary disease. Statistical analysis was done with Minitab 15 software. Descriptive statistics were summarized as mean, standard deviation, and percentage. Student's t-test was used to determine the significance of normally distributed parametric values. Z-test was used for proportion. Statistical significance was accepted at P < 0.05. RESULTS: OT extubation was found to be safe as no patient had reintubation or respiratory insufficiency. None of the patients in either group had postoperative myocardial infarction, stroke, low cardiac output, mediastinitis, and renal failure. Hypothermia, blood transfusion, atrial fibrillation, and re-exploration did not occur. Intensive Care Unit length of stay was similar in the two groups. Discharge day is statistically significant (P = 0.001), with 5.66 days in the IE group and 6.36 days in the UFTA group. Time spent in the operating room at the end of surgery is statistically significant, with 14.03 min in UFTA group and 33.9 min in IE group. CONCLUSION: IE appears to be safe and effective in OPCAB patients without any major complications. It can be achieved after fulfilling traditional extubation criteria but is confined to highly selective group of patients. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5914211/ /pubmed/29652272 http://dx.doi.org/10.4103/aca.ACA_135_17 Text en Copyright: © 2018 Annals of Cardiac Anaesthesia http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Nagre, Amarja Sachin
Jambures, Nagesh P
Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery
title Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery
title_full Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery
title_fullStr Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery
title_full_unstemmed Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery
title_short Comparison of Immediate Extubation Versus Ultrafast Tracking Strategy in the Management of Off-Pump Coronary Artery Bypass Surgery
title_sort comparison of immediate extubation versus ultrafast tracking strategy in the management of off-pump coronary artery bypass surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914211/
https://www.ncbi.nlm.nih.gov/pubmed/29652272
http://dx.doi.org/10.4103/aca.ACA_135_17
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