Dual-targeting biomimetic delivery for anti-glioma activity via remodeling the tumor microenvironment and directing macrophage-mediated immunotherapy

Tumor-associated macrophages (TAMs) are the major components in the tumor microenvironment (TME). The polarization from the protumor M2 (TAM2) to antitumor M1 (TAM1) phenotype can not only lift the immunosuppressive constraints and elicit cytotoxic T-cell immunity but also augment the chemotherapy e...

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Detalles Bibliográficos
Autores principales: Zhao, Pengfei, Wang, Yonghui, Kang, Xuejia, Wu, Aihua, Yin, Weimin, Tang, Yisi, Wang, Jinyu, Zhang, Meng, Duan, Yifei, Huang, Yongzhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914428/
https://www.ncbi.nlm.nih.gov/pubmed/29732051
http://dx.doi.org/10.1039/c7sc04853j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914428/
https://www.ncbi.nlm.nih.gov/pubmed/29732051
http://dx.doi.org/10.1039/c7sc04853j

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