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Design, synthesis, and structure–activity relationships of 2-benzylidene-1-indanone derivatives as anti-inflammatory agents for treatment of acute lung injury

PURPOSE: The purpose of this study was to design and synthesize novel 2-benzylidene-1-indanone derivatives for treatment of acute lung injury. METHODS: A series of 39 novel 2-benzylidene-indanone structural derivatives were synthesized and evaluated for anti-inflammatory activity in lipopolysacchari...

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Detalles Bibliográficos
Autores principales:	Xiao, Siyang, Zhang, Wenxin, Chen, Hongjin, Fang, Bo, Qiu, Yinda, Chen, Xianxin, Chen, Lingfeng, Shu, Sheng, Zhang, Yali, Zhao, Yunjie, Liu, Zhiguo, Liang, Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914570/ https://www.ncbi.nlm.nih.gov/pubmed/29719375 http://dx.doi.org/10.2147/DDDT.S160314

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