microRNA-26a induces a mitochondrial apoptosis mediated by p53 through targeting to inhibit Mcl1 in human hepatocellular carcinoma

AIM: We have previously found that microRNA-26a (miR-26a) is a potential tumor suppressor in hepatocellular carcinoma (HCC). In this study, we further explored the roles of miR-26a in HCC apoptosis. METHODS: miR-26a expression levels were detected in HCC tissues by real-time PCR. Statistical analysi...

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Detalles Bibliográficos
Autores principales: Gao, Xiao-Mei, Zhu, Ying, Li, Jian-Hua, Wang, Xiang-Yu, Zhang, Xiao-Fei, Yi, Chen-He, Yang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914889/
https://www.ncbi.nlm.nih.gov/pubmed/29719405
http://dx.doi.org/10.2147/OTT.S160895

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