HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution

In recent years, the lysosome has emerged as a highly dynamic, transcriptionally regulated organelle that is integral to nutrient-sensing and metabolic rewiring. This is coordinated by a lysosome-to-nucleus signaling nexus in which MTORC1 controls the subcellular distribution of the microphthalmia-t...

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Detalles Bibliográficos
Autores principales: Tol, Marc J., van der Lienden, Martijn J.C., Gabriel, Tanit L., Hagen, Jacob J., Scheij, Saskia, Veenendaal, Tineke, Klumperman, Judith, Donker-Koopman, Wilma E., Verhoeven, Arthur J., Overkleeft, Hermen, Aerts, Johannes M., Argmann, Carmen A., van Eijk, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Papers - Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915011/
https://www.ncbi.nlm.nih.gov/pubmed/29455584
http://dx.doi.org/10.1080/15548627.2017.1419118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915011/
https://www.ncbi.nlm.nih.gov/pubmed/29455584
http://dx.doi.org/10.1080/15548627.2017.1419118

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