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HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution
In recent years, the lysosome has emerged as a highly dynamic, transcriptionally regulated organelle that is integral to nutrient-sensing and metabolic rewiring. This is coordinated by a lysosome-to-nucleus signaling nexus in which MTORC1 controls the subcellular distribution of the microphthalmia-t...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915011/ https://www.ncbi.nlm.nih.gov/pubmed/29455584 http://dx.doi.org/10.1080/15548627.2017.1419118 |