Endonuclease G promotes mitochondrial genome cleavage and replication

Endonuclease G (EndoG) is a nuclear-encoded endonuclease, mostly localised in mitochondria. In the nucleus EndoG participates in site-specific cleavage during replication stress and genome-wide DNA degradation during apoptosis. However, the impact of EndoG on mitochondrial DNA (mtDNA) metabolism is...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiehe, Rahel Stefanie, Gole, Boris, Chatre, Laurent, Walther, Paul, Calzia, Enrico, Ricchetti, Miria, Wiesmüller, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915074/
https://www.ncbi.nlm.nih.gov/pubmed/29719607
http://dx.doi.org/10.18632/oncotarget.24822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915074/
https://www.ncbi.nlm.nih.gov/pubmed/29719607
http://dx.doi.org/10.18632/oncotarget.24822

Ejemplares similares