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Distribution of erlotinib in rash and normal skin in cancer patients receiving erlotinib visualized by matrix assisted laser desorption/ionization mass spectrometry imaging
BACKGROUND: The development of skin rashes is the most common adverse event observed in cancer patients treated with epidermal growth factor receptor-tyrosine kinase inhibitors such as erlotinib. However, the pharmacological evidence has not been fully revealed. RESULTS: Erlotinib distribution in th...
Autores principales: | Nishimura, Meiko, Hayashi, Mitsuhiro, Mizutani, Yu, Takenaka, Kei, Imamura, Yoshinori, Chayahara, Naoko, Toyoda, Masanori, Kiyota, Naomi, Mukohara, Toru, Aikawa, Hiroaki, Fujiwara, Yasuhiro, Hamada, Akinobu, Minami, Hironobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915091/ https://www.ncbi.nlm.nih.gov/pubmed/29719624 http://dx.doi.org/10.18632/oncotarget.24928 |
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