Cargando…
Improvement of non-alcoholic steatohepatitis by hepatocyte-like cells generated from iPSCs with Oct4/Sox2/Klf4/Parp1
The prevalence of nonalcoholic fatty liver disease (NAFLD) is usually increased with age. Non-alcoholic steatohepatitis (NASH), a serious form of NAFLD, may lead to cirrhosis and end-stage liver diseases. Induced pluripotent stem cells (iPSCs) hold promising potential in personalized medicine. Altho...
Autores principales: | Chien, Yueh, Huang, Chi-Shuan, Lin, Hsin-Chi, Lu, Kai-Hsi, Tsai, Ping-Hsing, Lai, Ying-Hsiu, Chen, Kuan-Hsuan, Lee, Shou-Dong, Huang, Yi-Hsiang, Wang, Chien-Ying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915096/ https://www.ncbi.nlm.nih.gov/pubmed/29719629 http://dx.doi.org/10.18632/oncotarget.23603 |
Ejemplares similares
-
Manipulation of KLF4 Expression Generates iPSCs Paused at Successive Stages of Reprogramming
por: Nishimura, Ken, et al.
Publicado: (2014) -
Excluding Oct4 from Yamanaka Cocktail Unleashes the Developmental Potential of iPSCs
por: Velychko, Sergiy, et al.
Publicado: (2019) -
iPSCs are safe!
por: Yan, Hualong, et al.
Publicado: (2017) -
Application of the Yamanaka Transcription Factors Oct4, Sox2, Klf4, and c-Myc from the Laboratory to the Clinic
por: Aguirre, Marisol, et al.
Publicado: (2023) -
Expression and Functional Analysis of core stemness factors OSKM (OCT4, SOX2, KLF4, and MYC) in Pan-cancer
por: Hong, Liwei, et al.
Publicado: (2023)