BRCA1/2 and TP53 mutation status associates with PD-1 and PD-L1 expression in ovarian cancer

Checkpoint molecules such as programmed cell death protein-1 (PD-1) and its ligand PD-L1 are critically required for tumor immune escape. The objective of this study was to investigate tumoral PD-1 and PD-L1 mRNA-expression in a cohort of ovarian cancer (OC) patients in relation to tumor mutations....

Descripción completa

Detalles Bibliográficos
Autores principales: Wieser, Verena, Gaugg, Inge, Fleischer, Martina, Shivalingaiah, Giridhar, Wenzel, Soeren, Sprung, Susanne, Lax, Sigurd F., Zeimet, Alain G., Fiegl, Heidelinde, Marth, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915132/
https://www.ncbi.nlm.nih.gov/pubmed/29707124
http://dx.doi.org/10.18632/oncotarget.24770

Ejemplares similares

Ejemplares similares