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Capecitabine reverses tumor escape from anti-VEGF through the eliminating CD11b(high)/Gr1(high) myeloid cells

The anti-VEGF humanized antibody bevacizumab suppresses various malignancies, but tumors can acquire drug resistance. Preclinical studies suggest myeloid-derived suppressor cells (MDSCs) may be associated with tumor refractoriness to anti-VEGF treatment. Here we report a novel mechanism of tumor esc...

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Detalles Bibliográficos
Autores principales:	Iwai, Toshiki, Harada, Yui, Saeki, Hiroshi, Oki, Eiji, Maehara, Yoshihiko, Yonemitsu, Yoshikazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915143/ https://www.ncbi.nlm.nih.gov/pubmed/29707135 http://dx.doi.org/10.18632/oncotarget.24811

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