PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERα serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer

Although endocrine therapy is the most important treatment option in estrogen receptor (ER)-positive breast cancer, new strategies, such as molecular targeted agents together with endocrine therapy are required to improve survival. PIK3CA is the most frequent mutated gene in ER-positive early breast...

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Detalles Bibliográficos
Autores principales: Ishida, Naoko, Baba, Motoi, Hatanaka, Yutaka, Hagio, Kanako, Okada, Hiromi, Hatanaka, Kanako C., Togashi, Kenichi, Matsuno, Yoshihiro, Yamashita, Hiroko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915150/
https://www.ncbi.nlm.nih.gov/pubmed/29707142
http://dx.doi.org/10.18632/oncotarget.24845

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