Circulating tumor DNA in early response assessment and monitoring of advanced colorectal cancer treated with a multi-kinase inhibitor

Predictive biomarkers are eagerly awaited in advanced colorectal cancer (aCRC). Targeted sequencing performed on tumor and baseline plasma samples in 20 patients with aCRC treated with regorafenib identified 89 tumor-specific mutations of which ≥50% are also present in baseline plasma. Droplet digit...

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Detalles Bibliográficos
Autores principales: Vandeputte, Caroline, Kehagias, Pashalina, El Housni, Hakim, Ameye, Lieveke, Laes, Jean-François, Desmedt, Christine, Sotiriou, Christos, Deleporte, Amélie, Puleo, Francesco, Geboes, Karen, Delaunoit, Thierry, Demolin, Gauthier, Peeters, Marc, D’Hondt, Lionel, Janssens, Jos, Carrasco, Javier, Marechal, Raphaël, Galdon, Maria Gomez, Heimann, Pierre, Paesmans, Marianne, Flamen, Patrick, Hendlisz, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915153/
https://www.ncbi.nlm.nih.gov/pubmed/29707145
http://dx.doi.org/10.18632/oncotarget.24879

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